斑马鱼抗体IL 1β Rabbit Polyclonal Antibody

Attribute:

Rabbit   Polyclonal  Antibody

Isotype:

Polyclonal

Purity:

Antigen Affinity Purification

Application:

ELISA, WB, IP

Calculated MW:

30kDa

Observed MW:

30kDa; 20kDa;   18kDa

Reactivity：

Zebra Fish

Immunogen：

Recombinant ZebraFish   IL 1β protein expressed by  E.Coli   

Buffer：

PBS with 0.1% sodium azide and 50% glycerol,  pH 7.2

Storage:

Store at -20℃.   Do not aliquot

Recommended Dilution:

WB: 1:1000-2000

IP: 1:5000-10000

IF: 1:100-200

Background：

There   are two genes for interleukin-1 : IL-1 alpha and IL-1 beta. IL-1β precursor   is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase) to form   mature IL-1β.  The multiple biologic   activities that define IL1 are properties of a 15- to 18-kD protein that is   derived from a 30- to 35-kD precursor. It is a pro-inflammatory cytokine   against infection, playing an important role in the pathogenesis of cancers.   It signals through various adaptor proteins and kinases that lead to   activation of numerous downstream targets. The expression level of IL-1B is   very low.