肝素锂

性状

Appearance

白色或类白色粉末，有吸湿性，水中易溶

White or almost white powder,Hygroscopic

Freely soluble in water

白色或类白色粉末，有吸湿性，水中易溶

White or almost white powder,Hygroscopic

Freely soluble in water

鉴别

Identification

¹³C NMR Spectrum

应符合规定

Should complied

符合规定

complied

HPLC

应符合规定

Should complied

符合规定

complied

分子量分布Molecular distribution

M_w=7200~13500D

11200D

效价potency

Anti-FⅩa:≥180IU/mg

205IU/mg

核苷酸 Nucleotidic

A260≤0.20

A280≤0.15

A260≤0.18

A280≤0.12

酸碱度pH

5.0~7.5

6.34

蛋白质 Protein

≤2.0%

≤1.0%

重金属Heavy Metals

NMT 30ppm

符合规定

complied

干燥失重Loss on drying

NMT 5.0%

2.7%

细菌内毒素Bacterial endotoxins

0.03USP U

符合规定

complied