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可提供吸入气雾剂、吸入粉雾剂、吸入液体制剂、鼻喷雾剂CDMO/CMO服务，可已有项目转让或二次开发，可根据客户立项定制CDMO服务，可接受上述产品CMO业务
康替唑胺原料药，CAS112968-42-9康替唑胺起始物料，N-3-异恶唑氨基甲酸叔丁酯,CAS264600-97-7康替唑胺中间体4，1-（4-氨基-2,3,6-三氟苯基）-2,3-二氢吡啶-4（1H）-酮, CAS1112968-95-2项目名称杂质中文名称杂质英文名称CAS号货号康替唑铵三氟-4-硝基苯基哌啶酮Trifluoro-4-nitrophenylpiperidinone1112968-91-836-003康替唑铵三氟-4-硝基苯基哌啶烯酮1112968-93-0 36-004康替唑铵4-氨基三氟苯基吡啶酮4-aminotrifluorophenylpyridone1112968-95-236-002康替唑铵三氟-4-甲酸异丁酯哌啶烯酮Trifluoro-4-carboxylic acid isobutyl ester piperidinone36-005康替唑铵三氟-4-恶唑羟甲基哌啶烯酮Trifluoro-4-oxazole-hydroxymethylpiperidinone1112968-16-7 36-006康替唑铵三氟-4-恶唑甲磺酰基哌啶烯酮Trifluoro-4-oxazolylsulfonyl piperidinone36-007康替唑铵BOC-康替唑铵Boc-Contazolamide 36-008康替唑铵康替唑铵Contazolamide1112968-42-936-000
可提供、定制多种原料药杂质对照品：产品编号/货号产品中文名称产品英文名称产品关键词03-0021-[2-(2,4-二甲基-苯硫基)-苯基]-哌嗪，氢溴酸盐，异丙醇合物Vothixetine hydrobromide isopropanol compound杂质对照品；伏硫西汀03-004(3-溴苯基)(2,4-二甲基苯基)硫烷(3-bromophenyl)(2,4-dimethylphenyl)sulfane杂质对照品；伏硫西汀03-005(4-溴苯基)(2,4-二甲基苯基)硫烷(4-bromophenyl)(2,4-dimethylphenyl)sulfane杂质对照品；伏硫西汀03-008(2-溴苯基)(3,4-二甲基苯基)硫烷(2-bromophenyl)(3,4-dimethylphenyl)sulfane杂质对照品；伏硫西汀04-003E异构体3'-((2E)-2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazineyl)-2'-hydroxy-3-carboxylic acid杂质对照品；艾曲泊帕乙醇胺07-00121-羟基孕甾-1,4,9(11) ,16-四烯-3,20-二酮-21-醋酸酯21-hydroxyprogesterone-1,4,9 (11), 16-tetraene-3,20-dione-21-acetate杂质对照品；布地奈德07-0029α-溴-11β,16α,17α-三羟孕甾-1,4-二烯-3,20-二酮-21-醋酸酯9α-bromine-11β,16α,17α-trihydroxyprogesterone-1,4-diene-3,20-dione-21-acetate杂质对照品；布地奈德07-00311,16,17,21-四羟孕甾-1,4-二烯-3,20-二酮-21-醋酸酯11,16,17,21-tetrahydroxyprogesterone-1,4-diene-3,20-dione-21-acetate杂质对照品；布地奈德08-002（R）-5-[2-（5，6-二乙基二氢茚-2-基氨基）-1-羟乙基]-8-苄氧基-1H-喹啉-2-酮苯甲酸盐(R) -5-[2- (5, 6-diethyldihydroindene-2-amino) -1-hydroxyethyl] -8-benzoxy-1H-quinolin-2-keto benzoate杂质对照品；醋酸茚达特罗09-0021-甲基吡咯烷-3-基-2-环戊基-2-羟基-2-苯乙酸酯 5-硝基间苯二甲酸盐（GP-5NA）1-methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate 5-nitroisophthalate杂质对照品；格隆溴铵10-006(3AR, 3A'R,4S, 4'S,7R,7AS,7'R, 7a'S)-2-2'-)丁烷-1,4-二基)双)- 4,7-亚甲基-1H-异吲哚-1,3(2H)-二酮)(3aR,3a'R,4S,4'S,7R,7aS,7'R,7a'S)-2,2'-(butane-1,4-diyl)bis(hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione)10-007(3AR,4S,7R,7AS) -2-丁基-4,7-亚甲基-1H-异吲哚-1,3(2H)-二酮(3aR,4S,7R,7aS)-2-butylhexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione杂质对照品；枸橼酸坦度螺酮12-0069-氯-11β,17-二羟基-16α-甲基-3,20-二氧代孕甾-1,4-二烯-21-对甲苯磺酸酯9-Chloro-11β, 17-dihydroxy-16α - methyl-3,20-dioxyprogester-1,4-diene-21-p-toluenesulfonic acid ester杂质对照品；糠酸莫米松12-0079-氯-11β-羟基-16α-甲基-21-[(对甲苯磺酰)基]-3,20-二氧代孕甾-1,4-二烯-17-(2-糠酸酯)9-chloro-11β - hydroxy-16α - methyl-21- [(p-toluenesulfonyl)] -3,20-dioxyprogester-1,4-diene-17- (2-furoate)杂质对照品；糠酸莫米松12-0089-氯-11β,17-二羟基-16α-甲基-3,20-二氧代孕甾-1,4-二烯-21-(2-糠酸酯)9-Chloro-11β, 17-dihydroxy-16α - methyl-3,20-dioxyprogester-1,4-diene-21- (2-furoate)杂质对照品；糠酸莫米松13-0072-(苄氧基)-3-(2-(叔丁基氨基)-1-羟乙基)苯甲酸甲酯methyl 2-(benzyloxy)-3-(2-(tert-butylamino)-1-hydroxyethyl)benzoate杂质对照品；硫酸沙丁胺醇13-0092-(苄氧基)-5-(1,2-二羟乙基)苯甲酸甲酯methyl 2-(benzyloxy)-5-(1,2-dihydroxyethyl)benzoate杂质对照品；硫酸沙丁胺醇13-0102-(苄氧基)-5-(2-(叔丁基氨基)-1-羟乙基)苯甲酸2-(benzyloxy)-5-(2-(tert-butylamino)-1-hydroxyethyl)benzoic acid杂质对照品；硫酸沙丁胺醇14-002左旋氧苄基沙丁胺甲酸甲酯DBTA盐(R) -2- (benzyloxy) -5- (2- (tert butylamino) -1-hydroxyethyl) benzoate methyl ester semi (2,3-bis (benzoyloxy) succinate)杂质对照品；盐酸左沙丁胺醇14-003左旋氧苄基沙丁胺甲酸甲酯(R) -2- (benzyloxy) -5- (2- (tert butylamino) -1-hydroxyethyl) benzoate methyl ester杂质对照品；盐酸左沙丁胺醇21-0042-(1-(2-氧-2-((4-(4-(嘧啶-2-基)哌嗪-1-基)丁基)氨基)乙基)环戊基)乙酸丁酯2- (1- (2-Oxy-2- (4- (4- (pyrimidin-2-yl) piperazin-1-yl) butyl) amino) ethyl) cyclopentyl) butyl acetate杂质对照品；盐酸丁螺环酮21-0052-(1-(2-氧代-2-((4-(4-(嘧啶-2-基)哌嗪-1-基)丁基)氨基)乙基)环戊基)乙酸乙酯2- (1- (2-oxo-2- (4- (4- (pyrimidin-2-yl) piperazin-1-yl) butyl) amino) ethyl) cyclopentyl) ethyl acetate杂质对照品；盐酸丁螺环酮22-0052-(4-甲酰氨基苯基)丁酸2-(4-formamidophenyl)butanoic acid杂质对照品；吲哚布芬22-0102,2′-((4-(1-羧丙基)苯基)氮杂二酰基)二(亚甲基)二苯甲酸2,2'-(((4-(1-carboxypropyl)phenyl)azanediyl)bis(methylene))dibenzoic acid杂质对照品；吲哚布芬24-002(2-(4-甲基-2-苯基哌嗪-1-基)苯基)甲醇盐酸盐(2-(4-methyl-2-phenylpiperazin-1-yl)phenyl)methanol hydrochloride杂质对照品；盐酸米安色林24-003(2-(2-苯基哌嗪-1-基)苯基)甲醇(2-(2-phenylpiperazin-1-yl)phenyl)methanol杂质对照品；盐酸米安色林25-0071-(2-(N-甲基甲酰胺基)乙基)哌啶-4-基[1,1'-联苯]-2-基氨基甲酸酯1-(2-(N-methylformamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate杂质对照品；雷芬那辛25-0101-(2-(乙基(甲基)氨基)乙基)哌啶-4-基[1,1'-联苯]-2-基氨基甲酸酯1-(2-(ethyl(methyl)amino)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate杂质对照品；雷芬那辛25-0111-(2-(异丙基(甲基)氨基)乙基)哌啶-4-基[1,1'-联苯]-2-基氨基甲酸酯1-(2-(isopropyl(methyl)amino)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate杂质对照品；雷芬那辛25-0121-(2-(二甲氨基)乙基)哌啶-4-基[1,1'-联苯]-2-基氨基甲酸酯1-(2-(dimethylamino)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate杂质对照品；雷芬那辛25-0141-(2-((4,6-二甲氧基-1,3,5-三嗪-2-基)(甲基)氨基)乙基)哌啶-4-基[1,1'-联苯]-2-基氨基甲酸酯1-(2-((4,6-dimethoxy-1,3,5-triazin-2-yl)(methyl)amino)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate杂质对照品；雷芬那辛25-0161-(4-甲酰基苯甲酰基)哌啶-4-基[1,1'-联苯]-2-基氨基甲酸酯1-(4-formylbenzoyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate杂质对照品；雷芬那辛25-0171-(4,6-二甲氧基-1,3,5-三嗪-2-基)哌啶-4-基[1,1'-联苯]-2-基氨基甲酸酯1-(4,6-dimethoxy-1,3,5-triazin-2-yl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate杂质对照品；雷芬那辛25-0181-（2-（N，4-二甲基苯甲酰胺基）乙基）哌啶-4-基[1，1'-联苯]-2-基氨基甲酸酯1-(2-(N,4-dimethylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate杂质对照品；雷芬那辛27-001反式-2-(4-氨基环己基)对甲苯磺酸乙酯Trans-2- (4-aminocyclohexyl) p-toluenesulfonic acid ethyl ester杂质对照品；盐酸卡利拉嗪27-0034-(2，3-二氯苯基)-1-(2-((1r，4r)-4-(3，3-二甲基脲基)环己基)乙基)哌嗪1-氧化物4- (2,3-dichlorophenyl) -1- (2- (((1r, 4r) -4- (3,3-dimethylurea) cyclohexyl) ethyl) piperazine 1-oxide杂质对照品；盐酸卡利拉嗪28-002氯代咪唑乙醇硫酸盐1-(2-chloro-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole sulfate杂质对照品；硝酸硫康唑28-0071-[2-(3-氯苄硫基)-2-(2,4-二氯苯基)乙基]-1H-咪唑1-[2-(3-Chlorobenzylthio)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole杂质对照品；硝酸硫康唑29-0014-苄氧基-3-硝基苯基环氧乙烷4-benzyloxy-3-nitrophenylepoxyethane杂质对照品；富马酸福莫特罗29-0024-苄氧基-3-氨基-α-[ N-苄基- N-（1-甲基-2-对甲氧基苯基乙基）氨基甲基]苄醇4-benzyloxy-3-amino-α-[N-benzyl-N-(1-methyl-2-p-methoxyphenylethyl) amino methyl] benzyl alcohol杂质对照品；富马酸福莫特罗29-0034-苄氧基-3-甲酰氨基-α-[ N-苄基- N-（1-甲基-2-对甲氧基苯基乙基）氨基甲基]苄醇富马酸盐4-benzyloxy-3-formylamino-α-[N-benzyl-N-(1-methyl-2-p-methoxyphenylethyl) amino methyl] benzyl alcohol fumarate salt杂质对照品；富马酸福莫特罗32-001去甲奈诺沙星(S)-7-(3-aminopiperidin-1-yl)-1-cyclopropyl-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid杂质对照品；苹果酸奈诺沙星33-001[(Z)-(2,4-二氟苯基)(六氢吡啶-4-基)甲亚基]羟胺盐酸盐(Z)-(2,4-difluorophenyl)(piperidin-4-yl)methanone oxime杂质对照品；帕利哌酮33-0033-(2-{4-[(2,4-二氟苯基)羰基]六氢吡啶-1-基}乙基)-9-羟基-2-甲基-6,7,8,9-四氢-4H-吡啶并[1,2-a]嘧啶-4-酮3-(2-(4-(2,4-difluorobenzoyl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one杂质对照品；帕利哌酮
可提供吸入制剂（吸入气雾剂、吸入粉雾剂、吸入液体制剂、鼻喷雾剂）CDMO服务，我公司具有15年以上吸入制剂开发、生产经验，可CDMO/CMO，可技术转让。我公司在CNS领域也有10年以上开发、生产经验，可为客户提供多个产品开发。外用制剂同样专业，目前我们已经为客户开发米诺地尔搽剂、米诺地尔泡沫剂等产品。可接受以下剂型的CDMO/CMO委托：n 吸入混悬液/吸入溶液（瑞士Rommelag 460/321型BFS一体机）（含激素类）n 吸入粉雾剂（德国瀚辉（HH）胶囊充填机、贮库型充填机）n 吸入气雾剂（瑞士Pamasol一步法、二步法灌装线）（含激素类）n 鼻喷雾剂（含激素类）n 口服液（溶液、混悬液、乳剂）/口腔喷雾剂/滴剂（高速均质，多规格瓶型）n 外用液体制剂/泡沫剂（防爆设计）n 外用气雾剂（可充氮，一步法、两步法，防爆设计）n 小容量注射剂（可充氮，终端灭菌，多规格玻璃安瓿）有意者请联系：18653879360（微信同号）
可转让现有进度项目，可申报或获批后转让。项目经验丰富，研究内容充分，可保证数据可靠性。本公司都有相应生产线，可受托加工。可现有进度转让，可接受委托CDMO/CMO。转让项目列表如下：项目名称化药注册分类适应症酒石酸阿福特罗雾化吸入溶液3COPD丙酸氟替卡松雾化吸入用混悬液4哮喘利多卡因丙胺卡因气雾剂3早泄丙酸氟替卡松鼻喷剂4过敏性鼻炎盐酸氮䓬斯汀鼻喷雾剂4过敏性鼻炎糠酸氟替卡松鼻用喷雾剂4过敏性鼻炎布地奈德鼻喷雾剂4过敏性鼻炎盐酸左西替利嗪口服滴剂4过敏性鼻炎盐酸氨溴索滴剂3痰液粘稠不易咳出氨溴特罗口服溶液3祛痰止咳平喘硫酸镁钠钾口服用浓溶液4检查或术前肠道清洁丙戊酸钠口服溶液4癫痫丙戊酸钠缓释片4癫痫拉莫三嗪片4癫痫米氮平片4抑郁症马来酸氟伏沙明片4抑郁症盐酸帕罗西汀肠溶缓释片4抑郁症阿立哌唑片4精神分裂症盐酸鲁拉西酮片4精神分裂症布瑞哌唑片3精神分裂症盐酸卡利拉嗪胶囊3精神分裂症盐酸美金刚缓释胶囊3阿尔茨海默型痴呆米诺地尔搽剂3男性型脱发和斑秃米诺地尔泡沫剂3男性型脱发和斑秃联苯苄唑溶液3皮肤真菌病有意者请联系：18653879360（微信同号）
项目名称杂质中文名称杂质英文名称CAS号货号左西孟旦杂质(S)-N-(4-(4-甲基-6-氧代-1,4,5,6-四氢哒嗪-3-基)苯基)羰基亚肼基丙二腈(S)-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide144238-75-534-001左西孟旦杂质(R)-2-氨基-N-(4-(4-甲基-6-氧代-1,4,5,6-四氢哒嗪-3-基)苯基)-2-氧代乙酰肼基氰化物(R,E)-2-amino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl cyanide274263-65-934-002左西孟旦杂质(R)-N-(4-(4-甲基-6-氧代-1,4,5,6-四氢哒嗪-3-基)苯基)羰基亚肼基丙二酰胺(R)-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazineylidene)malonamide N/A34-003左西孟旦杂质(E)-3-(氰基((E)-(4-((R)-4-甲基-6-氧代-1,4,5,6-四氢哒嗪-3-基)苯基)二氮烯基)亚甲基)-5-亚氨基-2-(4-(R)4-甲基-6-氧基-1,4,5,5-四氢哒肼-3-基)苯基)-2,3,4,5-四氢-1,2,4-三嗪-6-腈(E)-3-(cyano((E)-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)methylene)-5-imino-2-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile N/A34-004非奈利酮杂质4-（4-氰基-2-甲氧基苯基）-5-乙氧基-2,8-二甲基-1,4-二氢-1,6-萘啶-3-羧酸乙酯1,6-Naphthyridine-3-carboxylic acid, 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-, ethyl ester,N/A35-001非奈利酮杂质4-（4-氰基-2-甲氧基苯基）-5-乙氧基-2,8-二甲基-1,6-萘啶-3-酰胺4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,6-naphthyridine-3-carboxamide2084136-51-435-002非奈利酮杂质2-氰基乙基-4-(4-氰基-2-甲氧苯基)-2,8-二甲基-5-异丙氧基-1,4-二氢-1,6-萘啶-3-羧酸酯2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-5-isopropoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylateN/A35-003非奈利酮杂质2-氰基乙基-4-（4-氰基-2-甲氧基苯基）-5-甲氧基-2,8-二甲基-1,4-二氢-1,6-萘啶-3-羧酸酯2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-5-methoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylateN/A35-004非奈利酮杂质4-（4-氰基-2-甲氧基苯基）-5-异丙氧基-2,8-二甲基-1,4-二氢-1,6-萘啶-3-羧酸4-(4-cyano-2-methoxyphenyl)-5-isopropoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid2640280-87-935-005非奈利酮杂质4-（4-氰基-2-甲氧基苯基）-5-甲氧基-2,8-二甲基-1,4-二氢-1,6-萘啶-3-羧酸4-(4-cyano-2-methoxyphenyl)-5-methoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid2640280-86-835-006非奈利酮杂质2-氰基乙基-4-(4-氰基-2-甲氧基苯基)-5-乙氧基-2,8-二甲基-1,6-萘啶-3-羧酸酯2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,6-naphthyridine-3-carboxylate2924224-42-835-007非奈利酮杂质4-（4-氰基-2-甲氧基苯基）-5-异丙氧基-2,8-二甲基-1,4-二氢-1,6-萘啶-3-酰胺4-(4-cyano-2-methoxyphenyl)-5-isopropoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide2640280-85-735-008非奈利酮杂质4-（4-氰基-2-甲氧基苯基）-5-乙氧基-2,8-二甲基-1,6-萘啶-3-羧酸4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,6-naphthyridine-3-carboxylic acidN/A35-009非奈利酮杂质4-（4-氰基-2-甲氧基苯基）-5-甲氧基-2,8-二甲基-1,4-二氢-1,6-萘啶-3-酰胺4-(4-cyano-2-methoxyphenyl)-5-methoxy-2,8-dimethyl-1,4-dihydro- 1,6-naphthyridine-3-carboxamide2640280-84-635-010非奈利酮杂质2-氰基乙基 4-（4-氰基-2-甲氧基苯基）-2,8-二甲基-5-氧代-5,6-二氢-1,6-萘啶-3-羧酸酯2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-5,6-dihydro-1,6-naphthyridine-3-carboxylateN/A35-011非奈利酮杂质4-(5-乙氧基-3-(1H-咪唑-1-羰基)-2,8-二甲基-1,4-二氢-1,6-萘啶-4-基)-3-甲氧基苯腈4-(5-ethoxy-3-(1H-imidazole-1-carbonyl)-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-4-yl)-3-methoxybenzonitrile1050477-58-135-012非奈利酮杂质(R)-4-(4-氰基-2-甲氧苯基)-5-乙氧基-2,8-二甲基-1,4-二氢-1,6-萘啶-3-甲酰胺 (R)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide1050477-30-935-013
