目录号：BY10018产品名称：WZ4002英文名：WZ4002别名：CHEBI:61400; N-(3-(5-chloro-2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yloxy)phenyl)acrylamide; WZ-4002;IUPAC Name:N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamideCAS号：1213269-23-8分子式：C25H27ClN6O3分子量：494.18纯度：99%+供应能力：克用途：科研实验参考信息InChI Key:ITTRLTNMFYIYPA-UHFFFAOYSA-NReaxys Registry Number:20845904Pub CID:44607530Canonical SMILES:CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl)OCReferences:ACEA BIOSCIENCES INC.; XU, Xiao; WANG, Xiaobo; MAO, Long; ZHAO, Li; XI, Biao; XU, Wanhong; TANG, Wei Patent: WO2013/106792 A1, 2013 ;Han, Chun; Huang, Zhangjian; Zheng, Chao; Wan, Ledong; Zhang, Lianwen; Peng, Sixun; Ding, Ke; Ji, Hongbin; Tian, Jide; Zhang, Yihua Journal of Medicinal Chemistry, 2013 , vol. 56, # 11 p. 4738 - 4748；Zhou, Wei; Liu, Xiaofeng; Tu, Zhengchao; Zhang, Lianwen; Ku, Xin; Bai, Fang; Zhao, Zhenjiang; Xu, Yufang; Ding, Ke; Li, Honglin Journal of Medicinal Chemistry, 2013 , vol. 56, # 20 p. 7821 - 7837;

目录号：BY00003产品名称：Rociletinib英文名：Rociletinib别名：CO-1686IUPAC Name:N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamideCAS号：1374640-70-6分子式：C27H28F3N7O3分子量：555.55纯度：99%+供应能力：毫克到公斤级参考信息InChI Key:HUFOZJXAKZVRNJ-UHFFFAOYSA-NReaxys Registry Number:23999130Pub CID:57335384Canonical SMILES:CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)C(F)(F)F)OCReferences:Patent; CELGENE AVILOMICS RESEARCH, INC.; LAI, Mei; WO2013/138495; A1; (2013);

目录号：BY00035产品名称：阿法替尼英文名：BIBW 2992别名：Afatinib; Tovok; BIBW2992; TomtovokIUPAC Name:(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamideCAS号：439081-18-2分子式：C24H25ClFN5O3分子量：485.944纯度：99%+供应能力：克用途：科研实验参考信息InChI Key:ULXXDDBFHOBEHA-CWDCEQMOSA-NReaxys Registry Number:N/APub CID:10184653Canonical SMILES:CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4References:N/A

目录号：BY30118产品名称：AZD3759英文名：AZD3759别名：AZD-3759; (R)-4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate;UNII-67SX9H68W2; SCHEMBL16010006IUPAC Name:[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl] (2R)-2,4-dimethylpiperazine-1-carboxylateCAS号：1626387-80-1分子式：C22H23ClFN5O3分子量：459.91纯度：99%+供应能力：毫克到克用途：科研实验参考信息InChI Key:MXDSJQHFFDGFDK-CYBMUJFWSA-NReaxys Registry Number:N/APub CID:78209992Canonical SMILES:CC1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)CReferences:N/A

目录号：BY00024产品名称：阿法替尼双马来酸盐英文名：Afatinib dimaleate别名：BIBW 2992MA2IUPAC Name:(Z)-but-2-enedioic acid;(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamideCAS号：850140-73-7分子式：C24H25ClFN5O3.2(C4H4O4)分子量：718.09纯度：99%+供应能力：毫克到公斤级参考信息InChI Key:USNRYVNRPYXCSP-JUGPPOIOSA-NReaxys Registry Number:N/APub CID:15606394Canonical SMILES:CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)OReferences:N/A

目录号：BY10020产品名称：苯扎米特英文名：INC 280 (INCB28060)别名：Capmatinib; 2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide; INC-280;UNII-TY34L4F9OZIUPAC Name:2-fluoro-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]-N-(trideuteriomethyl)benzamideCAS号：1029712-80-8分子式：C23H17FN6O分子量：416.430223纯度：99%+供应能力：克用途：科研实验参考信息InChI Key:LIOLIMKSCNQPLV-KQORAOOSSA-NReaxys Registry Number:18352802Pub CID:91971812Canonical SMILES:CNC(=O)C1=C(C=C(C=C1)C2=NN3C(=CN=C3N=C2)CC4=CC5=C(C=C4)N=CC=C5)FReferences:Patent; NOVARTIS AG; CAPONIGRO, Giordano; HUANG, Xizhong; LEHAR, Joseph; WANG, Hui-Qin; WO2014/28566; (2014); A1; Patent; NOVARTIS AG; PORTER, Dale; EMERY, Caroline; TAN, Lujian; WO2014/174478; (2014); A1; Patent; NOVARTIS AG; TIEDT, Ralph; CHATENAY-RIVAUDAY, Christian; ITO, Moriko; PENG, Bin; GONG, Ying; AKIMOV, Mikhail; WO2013/149581; (2013); A1;Patent; Weng, Lingkai; Qiao, Lei; Zhou, Jiacheng; Liu, Pingli; Pan, Yongchun; US2009/291956; (2009); A1;Patent; INCYTE CORPORATION; ZHUO, Jincong; METCALF, Brian; WO2008/64157; (2008); A1;

目录号：BY00009产品名称：AZD-9291英文名：AZD-9291别名：AZD 9291; Osimertinib; AZD9291; MereletinibIUPAC Name:N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamideCAS号：1421373-65-0分子式：C28H33N7O2分子量：499.61纯度：99.5%+供应能力：毫克到克用途：科研实验参考信息InChI Key:DUYJMQONPNNFPI-UHFFFAOYSA-NReaxys Registry Number:23334373Pub CID:71496458Canonical SMILES:CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OCReferences:N/A

目录号：BY00021产品名称：卡博替尼英文名：Cabozantinib(XL184)别名：[14C]-Cabozantinib; Cabozantinib; cyclopropane- 1,1-dicarboxylic acid [4-(6,7-dimethoxy-quinoline-4-yloxy)-phenyl]-amide (4-fluoro-phenyl)-amide; cyclopropane-1,1-dicarboxylicacid [4-(6,7-dimethoxy-quinoline-4-yloxy)phenyl]amide(4-fluorophenyl)amide; cyclopropane-1,1-dicarboxylic acid [4-(6,7-dimethoxyquinoline-4-yloxy)phenyl]amide(4-fluorophenyl)amide; Cometriq?; cabozantinibIUPAC Name:1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1- N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideCAS号：849217-68-1分子式：C28H24FN3O5分子量：502纯度：99%+供应能力：克到公斤级参考信息InChI Key:ONIQOQHATWINJY-UHFFFAOYSA-NReaxys Registry Number:18631644Pub CID:25102847Canonical SMILES:COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O) NC5=CC=C(C=C5)FReferences:Article; She, Nengfang; Zhuo, Linsheng; Jiang, Wen; Zhu, Xiaolei; Wang, Jia; Ming, Zhihui; Zhao, Xinge; Cong, Xin; Huang, Wei; Bioorganic and Medicinal Chemistry Letters; vol. 24; 15; (2014); p. 3351 - 3355;Patent; EXELIXIS, INC.; SWEENEY, Christopher J.; KANTOFF, Philip W.; WO2014/165779; (2014); A1;Article; Jiang, Xiaolong; Liu, Hongyan; Song, Zilan; Peng, Xia; Ji, Yinchun; Yao, Qizheng; Geng, Meiyu; Ai, Jing; Zhang, Ao; Bioorganic and Medicinal Chemistry; vol. 23; 3; (2015); p. 564 - 578;Patent; EXELIXIS, INC.; AFTAB, Dana, T; SCHIMMOLLER, Frauke; WO2013/70890; (2013); A1;Patent; EXELIXIS, INC.; AFTAB, Dana, T.; WO2013/166296; (2013); A1;Patent; EXELIXIS, INC.; DECILLIS, Arthur; WO2014/165786; (2014); A1;Patent; EXELIXIS, INC.; AFTAB, Dana, T.; NAGANATHAN, Sriram; XU, Wei; LACY, Steven; NGUYEN, Linh; WO2014/145715; (2014); A1;Patent; EXELIXIS, INC.; WILSON, Jo, Ann; NAGANATHAN, Sriram; PFEIFFER, Matthew; ANDERSEN, Neil, G.; WO2013/59788; (2013); A1;Patent; EXELIXIS, INC.; AFTAB, Dana, T.; CLARY, Douglas; WO2013/43840; (2013); A1;Patent; EXELIXIS, INC.; WILSON, Jo Ann; WO2012/109510; (2012); A1;

目录号：BY10012产品名称：达克替尼英文名：Dacomitinib别名：PF299804; C24H25ClFN5O2; UNII-2XJX250C20; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamideIUPAC Name:(E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamideCAS号：1110813-31-4分子式：C24H25ClFN5O2分子量：469.9390032纯度：99%+供应能力：克用途：科研实验参考信息InChI Key:LVXJQMNHJWSHET-AATRIKPKSA-NReaxys Registry Number:N/APub CID:11511120Canonical SMILES:COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)C=CCN4CCCCC4References:N/A

目录号：BY00027产品名称：AP26113英文名：AP26113别名：UNII-3DGD69C6PV; ALK-IN-1; 3DGD69C6PV; C26H34ClN6O2PIUPAC Name:5-chloro-2-N-[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl]-4-N-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamineCAS号：1197958-12-5分子式：C27H36ClN6O4P分子量：575.039301纯度：99%+供应能力：克用途：科研实验参考信息InChI Key:OVDSPTSBIQCAIN-UHFFFAOYSA-NReaxys Registry Number:N/APub CID:57390074Canonical SMILES:CN(C)C1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4P(=O)(C)C)Cl)OCReferences:N/A