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| Catalogue number: | A767505 |
| Chemical name: | Arformoterol Tartrate |
| Synonyms: | N-[2-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino] ethyl]phenyl]formamide (+)-(2R,3R)-Tartaric Acid; (-)-Formoterol 1,2-Dihydroxyethane-1,2-dicarboxylic Acid; (R,R)-Formoterol Threaric Acid; Arformoterol d-Tartaric Acid; Arformoterol d-α,β-Dihydroxysuccinic Acid; |
| CAS Number: | 200815-49-2 |
| Possible CAS #: | NA |
| Molecular form.: | C₂₃H₃₀N₂O₁₀ |
| Appearance: | Off-White Solid |
| Melting Point: | 183-185°C |
| Mol. Weight: | 494.49 |
| Storage: | Refrigerator, Under Inert Atmosphere |
| Solubility: | DMSO |
| Stability: | No Data Available |
| Category: | Aromatics, Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, |
| Boiling Point: | No Data Available |
| Applications: | Arformoterol Tartrate, can be used in the synthesis of Omeprazole (O635000), which is a proton pump inhibitor, that inhibits gasteric secretion, also used in the treatment of dyspepsia, peptic ulcer disease, etc. Itis also the impurity of Esomeprazole Magnesium (E668300), which is the S-form of Omeprazole, and is a gastric proton-pump inhibitor. Also, It can be used for the preparation of olodaterol, a novel inhaled β2-adrenoceptor agonist with a 24h bronchodilatory efficacy. |
| References: | Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998); Stenhoff, H., et al.: J. Chromatogr., 734, 191 (1999), Johnson, D.A., et al.: Expert Opin. Pharmacother., 4, 253 (2003); Bouyssou, T., et al.: Bio. Med. Chem. Lett. 20, 1410, (2010); |
| Dangerous Goods Info: | NA |
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