药智官方微信 药智官方微博
客服 反馈

 凯立德生物医药技术(上海)有限公司(Chemleader Biomedical Co., Limited)成立于2010年, 是一家全球领先的科研化学品和生物活性化合物供应商。      公司总部位于上海张江高科技园区南区上海国际医学园区,公司专注于抗癌抗肿瘤药物科研试剂及生物活性化合物,致力打造高端医药研发试剂品牌,旨在为全球科研事业和工业领域客户提供系统的产品资源及配套技术服务。      公司6,000多种库存产品主要销往国内的诸多科研院所和大中院校以及欧美,东南亚等国家。凯立德生物的每一个产品都经过严格质量把控,每个产品在出库时都配有现批次的NMR核磁共振谱、HPLC、LC-MS以及产品分析报告单CoA等相关分析检测数据。     公司产品特色类别:肿瘤药物研究试剂、癌症研究试剂、干细胞研究试剂、生物活性小分子、多肽研究试剂、生物活性肽、药物杂质、天然产物(天然生物活性化合物、植物化学单体、药用植化单体(天然活性成分)、天然产物提取分离、天然产物合成、天然产物结构修饰、海洋活性分子定制合成。     公司主营产品线:生化试剂 & 合成砌块、抑制剂(信号通路抑制剂、抗生素和抗病毒研究抑制剂)、分子靶向药物活性化合物、高通量筛选试剂、小分子化合物库、药物筛选化合物库、天然产物对照品标准品、细胞凋亡及细胞信号转导、医药中间体、抗体、试剂盒。 定制服务:医药中间体定制合成、多肽定制合成、参考化合物定制合成、药物杂质定制合成等。 我们的优势:性价比高(国际化的品质 本土化的价格 )、品种齐全、质量保证、退换货无忧。

[更多详情]

热门供应

更多

Doxorubicin HydrochlorideCAS No.: 25316-40-9Formula: C₂₇H₃₀ClNO₁₁Molecular Weight: 579.98Biological Activity: Doxorubicin hydrochloride is a Topoisomerase II (Top2) catalytic inhibitor, also is a broad spectrum antibiotic used in the treatment of cancers, with IC50 of 374 nM for Hela cells.

TemoporfinCAS No.: 122341-38-2Formula: C44H32N4O4Molecular Weight: 680.75Biological Activity: Temoporfin is a synthetic light-activated chlorin with photodynamic activity. Upon systemic administration, temoporfin distributes throughout the body and is taken up by tumor cells. Upon stimulation of temoporfin by non-thermal laser light (at 652 nm), and in the presence of oxygen, this agent produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to tumor cells. This may kill tumor cells and may reduce the tumor size. Temoporfin(KW 2345) used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck.Patients can remain photosensitive for several weeks after treatment.

Belinostat (PXD101; PX105684)CAS: 866323-14-0Formula: C15H14N2O4SMolecular Weight: 318.35Biological Activity: Belinostat is a potent HDAC inhibitor with an IC50 of 27 nM in HeLa cell extracts.

TAK242; TAK 242;Resatorvid; 瑞沙托维; Resatorvid(TAK-242)CAS: 243984-11-4Formula: C15H17ClFNO4S                         Molecular Weight:  361.82Biological Activity: TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling. TAK-242 is in treatment of sepsis and septic shock.TAK-242 (resatorvid), a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, inhibits the production of lipopolysaccharide-induced inflammatory mediators by binding to the intracellular domain of TLR4.

Cyclopamine(11-Deoxyjervie)CAS:4449-51-8 Formula: C₂₇H₄₁NO₂                                           Molecular Weight:411.62Biological Activity:Cyclopamine is a Hedgehog (Hh) pathway antagonist with IC50 of 46 nM in the Hh cell assay.

最新供应

更多

Doxorubicin HydrochlorideCAS No.: 25316-40-9Formula: C₂₇H₃₀ClNO₁₁Molecular Weight: 579.98Biological Activity: Doxorubicin hydrochloride is a Topoisomerase II (Top2) catalytic inhibitor, also is a broad spectrum antibiotic used in the treatment of cancers, with IC50 of 374 nM for Hela cells.

TemoporfinCAS No.: 122341-38-2Formula: C44H32N4O4Molecular Weight: 680.75Biological Activity: Temoporfin is a synthetic light-activated chlorin with photodynamic activity. Upon systemic administration, temoporfin distributes throughout the body and is taken up by tumor cells. Upon stimulation of temoporfin by non-thermal laser light (at 652 nm), and in the presence of oxygen, this agent produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to tumor cells. This may kill tumor cells and may reduce the tumor size. Temoporfin(KW 2345) used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck.Patients can remain photosensitive for several weeks after treatment.

TAK242; TAK 242;Resatorvid; 瑞沙托维; Resatorvid(TAK-242)CAS: 243984-11-4Formula: C15H17ClFNO4S                         Molecular Weight:  361.82Biological Activity: TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling. TAK-242 is in treatment of sepsis and septic shock.TAK-242 (resatorvid), a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, inhibits the production of lipopolysaccharide-induced inflammatory mediators by binding to the intracellular domain of TLR4.

Cabazitaxel(XRP-6258); 卡巴他赛CAS: 183133-96-2Formula: C45H57NO14                             Molecular Weight:  835.93Biological Activity: Cabazitaxel is a semi-synthetic derivative of toxal, a natural taxoid microtubule inhibitor. Cabazitaxel has been shown to have antitumor activity in vitro, and while it has a lower affinity for the ATP-dependent efflux pump, P-glycoprotein 1 (P-gp) relative to toxal or docetaxel, it has shown greater ability to penetrate the blood-brain barrier than either. In mice and rat models, uptake of cabazitaxel has been shown to increase at concentrations above 11 μM and saturation has been seen at 13 μM. This seems to suggest that P-gp may be essential to transport cabazitaxel across the blood-brain barrier at specific threshold concentrations.

Cyclopamine(11-Deoxyjervie)CAS:4449-51-8 Formula: C₂₇H₄₁NO₂                                           Molecular Weight:411.62Biological Activity:Cyclopamine is a Hedgehog (Hh) pathway antagonist with IC50 of 46 nM in the Hh cell assay.